Nutritional Status and the Critically Ill Patient: Gut Microbiota and Immuno-Nutrition in I.C.U. at the Time of SARS-COV 2 Pandemic

Background: Gut microbiota is a complex ecosystem of bacteria, viruses, archaea, protozoa and yeasts in our intestine. It has several functions, including maintaining human body equilibrium. Microbial “dysbiosis” can be responsible for outbreak local systemic infections, especially critically ill patients. Methods: to build narrative review, we performed Pubmed, Medline EMBASE search English language papers, reviews, meta-analyses, case series randomized controlled trials (RCTs) by keywords their associations: patient; nutrition; gut microbiota; probiotics; virome; SARS-COV 2. Results: Over the antibiotic-based “selective decontamination”, potentially drug-resistant microorganisms development, there growing interest scientists pharmaceutical industry pre-, probiotics associations as safe reliable remedies restoring microbial “eubiosis”. Very first encouraging evidences link different profiles with 2 disease stage gravity. Thus, frame probiotic therapeutic approach COVID-19. Conclusions: remodulation seems promising prevent multi-resistant bug infections intensive care unit (ICU) This deserves more attention at time pandemic.